In addition, many stories such as our earlier investigation have also indicated that combination of hPK5 with other therapeutic agents, this sort of as ionizing radiation [26,28] and matrix metalloproteinase [29] could remarkably increase the antiangiogenic effect

In vivo panning of phage libraries in tumor-bearing animals has proved beneficial for selecting peptides capable to interact with proteins expressed within tumor-related vessels and to property to neoplastic tissues…