Further experiments applying exogeneous soluble NA revealed that essentially the most most likely mechanism for enhancement of fusion and infectivity by NA was related to desialylation of virion-expressed HA

onocytes had been isolated by gelatin adherence and permitted to differentiate in RPMI (Life Technologies) supplemented with 20% fetal bovine serum (FBS), 500U/ml granulocyte-macrophage colony-stimulating issue (GM-CSF), and 250 U/ml…