6-Chloropurine riboside – C14-demethylase

Product Name: 6-Chloropurine riboside

Synonym: 6-Chloropurine-9-β-D-ribofuranoside

CAS Number: 5399-87-1
Empirical Formula (Hill Notation): C₁₀H₁₁ClN₄O₄
Molecular Weight: 286.67
Beilstein Registry Number: 40573
EC Number: 226-438-4
MDL Number: MFCD00005738
Linear Formula: C₁₀H₁₁ClN₄O₄
Product Type: Chemical

CAS NO: 376640-41-4Bcr-Abl inhibitors
InChI Key
XHRJGHCQQPETRH-KQYNXXCUSA-N
mp
158-162 °C (dec.)(lit.)
Storage temp.: −20°C
Application: 6-Chloropurine riboside is used to study the kinetics and substrate specificity of adenosine deaminase. 6-Chloropurine riboside is benzoylated to facilitate synthesis of nucleoside derivatives such as 9-(2,3-Di-deoxy-2-fluoro-β-D-threo-pentofuranosyl)adenine. 6-Chloropurine riboside, especially after phosphorylation to NMP, NDP or NTP, is used as a purine substrate analogue in studies with enzymes such as Inosine monophosphate dehydrogenase (IMPDH); bacteriophage T4 RNA-ligase (EC 6.5.1.3) and pancreatic fibonuclease A.
RIDADR: NONH for all modes of transport
WGK Germany: 3
mp
158-162 °C (dec.)(lit.)
Storage Temp.: −20°C
UNSPSC
41106305
PubMed ID:http://jpet.aspetjournals.org/content/93/2/168