Product Name: Anti-CD3G (156-170) antibody produced in rabbit
Synonym: Anti-CD3γ; Anti-CD3G T-cell surface glycoprotein CD3γ chain precursor; Anti-T3G
Product Type: Chemical
CAS NO: 1108743-60-7PI3K_Akt_mTOR inhibitors
antibody Form: IgG fraction of antiserum
application(s)
western blot: 1:500-1:2,000
biological source
rabbit
clone
polyclonal
Conjugate: unconjugated
Form: buffered aqueous solution
Mol wt: antigen mol wt ~20 kDa
Shipped in: dry ice
species reactivity
human
Storage temp.: −20°C
Application: Anti-CD3G (156-170) antibody is suitable for western blot at a dilution of 1:500-1:2,000.
Yale Center for High Throughput Cell Biology IF-tested antibodies. Each antibody is tested by immunofluorescence against HUVEC cells using the Yale HTCB IF protocol. To learn more about the Sigma Life Science and Yale Center for High Throughput Cell Biology partnership, visit sigma.com/htcb-if.
Biochem/physiol Actions:
The pre-TCR–CD3 complex consists of pTα, TCR-β, and CD3 proteins. CD3 proteins are expressed in immature thymocytes, previous to TCR-β (T cell receptor-β), and pTα (pre-TCR-α). Later TCR-α replaces pTα and the resulting TCR–CD3 complex mediates signal transduction cascades followed by T cell development.
Features and Benefits:
Antibody Bioguarantee
Evaluate our antibodies with complete peace of mind. If the antibody does not perForm in your application, we will issue a full credit or replacement antibody. Learn more.
General description: CD3 protein, highly associated with the T cell receptor (TCR), is essential for the assembly and signal transduction of the T cell receptor on mature T cells. There are four copies of CD3 protein such as γ, δ, ε, ξ. CD3γ Forms heterodimer with CD3ε.
Immunogen:
synthetic peptide corresponding to amino acids 156-170 of human CD3G
Physical Form: Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide
RIDADR: NONH for all modes of transport
WGK Germany: 2
Storage Temp.: −20°C
UNSPSC
12352203
PubMed ID:http://jpet.aspetjournals.org/content/93/2/126