Product Name: Anti-CPN1 (186-199) antibody produced in rabbit
Synonym: Anti-CPN; Anti-CPN1 Carboxypeptidase N catalytic chain precursor; Anti-SCPN
Product Type: Chemical
CAS NO: 1030937-27-9FLAP inhibitors
antibody Form: IgG fraction of antiserum
application(s)
western blot: 1:500-1:2,000
biological source
rabbit
clone
polyclonal
Conjugate: unconjugated
Form: buffered aqueous solution
Mol wt: antigen mol wt ~52 kDa
Shipped in: dry ice
species reactivity
human
Storage temp.: −20°C
Application: Yale Center for High Throughput Cell Biology IF-tested antibodies. Each antibody is tested by immunofluorescence against HUVEC cells using the Yale HTCB IF protocol. To learn more about the Sigma Life Science and Yale Center for High Throughput Cell Biology partnership, visit sigma.com/htcb-if. Anti-CPN1 antibody produced in rabbit is suitable for western blotting at a working dilution of 1:500 to 1:2000.
Biochem/physiol Actions:
The enzyme is an anaphylatoxin inactivator and also regulates kinins. CPN binds to fibrinogen and is present in a fibrin clot prepared from plasma. Deficiency of CPN causes severe allergic syndrome.
Features and Benefits:
Antibody Bioguarantee
Evaluate our antibodies with complete peace of mind. If the antibody does not perForm in your application, we will issue a full credit or replacement antibody. Learn more.
General description: CPN1 is a metalloenzyme that preferentially cleaves C-terminal lysine and arginine residues from several proteins. CPN is a tetramer with two identical regulatory subunits and two identical catalytic subunits. This gene encodes a catalytic subunit.
Immunogen:
synthetic peptide corresponding to amino acids 186-199 of human CPN1
Physical Form: Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide
RIDADR: NONH for all modes of transport
WGK Germany: 2
Storage Temp.: −20°C
UNSPSC
12352203
PubMed ID:http://jpet.aspetjournals.org/content/96/2/145