Product Name: Anti-CX3CR-1, N-Terminal antibody produced in rabbit
MDL Number: MFCD02687272
Product Type: Chemical
CAS NO: 141396-28-3Itk inhibitors
antibody Form: affinity isolated antibody
application(s)
immunohistochemistry: 2 μg/mL using human heart tissue
western blot: 0.5-1 μg/mL using human spleen tissue lysate
biological source
rabbit
clone
polyclonal
Concentration: ~1 mg/mL
Conjugate: unconjugated
Form: buffered aqueous solution
Mol wt: antigen mol wt 50 kDa
Shipped in: dry ice
species reactivity
human, mouse, rat
Storage temp.: −20°C
Application: Anti-CX3CR-1, N-Terminal antibody is suitable for use in immunoblot (approx. 50kDa), western blot (0.5-1 μg/ml) using human spleen lysate) and immunohistochemistry (~2 μg/mL using human heart tissue).
General description: CX3CR1 is a fractalkaine receptor that regulates chemotaxis and adhesion in white blood cells . Impairment of CX3CR1 function has been associated with defects in hippocampal cognition and neuronal plasticity . Cells expressing CX3CR1 receptors inhibit T-cell proliferation and subsequently prevent intestinal inflammation . Anti-CX3CR-1, N-Terminal antibody is specific for CX3CR1 by immunoblotting using human spleen tissue lysate. The antibody also reacts with mouse and rat CX3CR1.
Immunogen:
synthetic peptide corresponding to the N-terminal and amino acids 2-21 of human CX3CR1 (V28, CMKBRL1). This sequence differs from mouse and rat by four amino acids.
Physical Form: Solution in 0.01 M phosphate buffered saline containing 0.02% sodium azide.
RIDADR: NONH for all modes of transport
WGK Germany: 2
Storage Temp.: −20°C
UNSPSC
51111800
PubMed ID:http://jpet.aspetjournals.org/content/93/2/230