Product Name: Anti-CXCR4 (Fusin) (182-196) antibody produced in rabbit
MDL Number: MFCD01092337
Product Type: Chemical
CAS NO: 14534-61-3IGF-1R inhibitors
antibody Form: IgG fraction of antiserum
application(s)
western blot: 0.5 – 1 μg/mL using human HeLa cell extract
biological source
rabbit
clone
polyclonal
Conjugate: unconjugated
Form: buffered aqueous solution
Shipped in: dry ice
species reactivity
human
Storage temp.: −20°C
Application: Anti-CXCR4 (Fusin) (182-196) antibody may be used in immunoblotting at a working antibody concentration of 0.5 – 1 μg/ml using human HeLa cell extract. It can also be used in immunohistochemistry.
General description: Chemokine receptor CXCR-4 also refers as fusin or LESTR is a protein that belongs to G-protein coupled receptor 1 family. It is an essential cofactor for T cell-tropic HIV viruses into CD4+ cells. N-Terminal domain and second extracellular loop of the protein act as a HIV binding sites. Anti-CXCR4 (Fusin) (182-196) antibody can be used to block HIV-1 and HIV-2 fusion and infection of human target cells. Rabbit anti-CXCR4 (Fusin) (182-196) antibody reacts specifically with human CXCR4.
Immunogen:
synthetic peptide corresponding to amino acids 182-196 of the second extracellular loop of human CXCR4.
Other Notes:
The antigen (receptor) is also termed fusin, LESTER and HUMSTR.
Physical Form: Solution in phosphate buffered saline containing 0.02% sodium azide.
RIDADR: NONH for all modes of transport
WGK Germany: 2
Storage Temp.: −20°C
UNSPSC
12352203
PubMed ID:http://jpet.aspetjournals.org/content/93/2/223