Product Name: Anti-Caspase 13 (ERICE) antibody produced in rabbit
MDL Number: MFCD02686011
Product Type: Chemical
CAS NO: 145225-02-1RIP kinase inhibitors
antibody Form: IgG fraction of antiserum
application(s)
microarray: suitable
western blot: 0.5-1 μg/mL using total HeLa cell lysate or rat or mouse brain lysates.
biological source
rabbit
clone
polyclonal
Concentration: ~0.5 mg/mL
Conjugate: unconjugated
Form: buffered aqueous solution
Mol wt: antigen mol wt 43 kDa
Shipped in: dry ice
species reactivity
rat, human, mouse
Storage temp.: −20°C
Application: Anti-Caspase 13 (ERICE) antibody is suitable western blot at a concentration of 0.5-1μg/mL using total HeLa cell lysate or rat or mouse brain lysates. It is also suitable for microarray.
Biochem/physiol Actions:
Caspases belongs to ICE (interleukin 1β-converting enzyme) family in almost 13 different Form. Caspase-13 (ERICE, evolutionary-related interleukin-1 β converting enzyme) is a recently discovered novel member of the caspase family. It is synthesized as inactive proenzymes comprising an N-terminal peptide (prodomain) including one large and one small subunit. It is expressed in a variety of human tissues and cell lines but mainly expressed in peripheral blood lymphocytes, spleen, and placenta. Overexpression of ERICE induces apoptosis of human embryonic kidney cells and breast carcinoma cells. Caspase-13 induces apoptosis. It is activated by caspase-8, which is a key enzyme in death receptor induced apoptosis.
Features and Benefits:
Antibody Bioguarantee
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Immunogen:
synthetic peptide corresponding to amino acids 91-105 of human caspase 13.
Physical Form: solution in phosphate buffered saline, containing 0.02% sodium azide.
WGK Germany: –
Storage Temp.: −20°C
UNSPSC
12352203
PubMed ID:http://jpet.aspetjournals.org/content/94/4/339