CPTH2

Product Name: CPTH2

Synonym: Cyclopentylidene-[4-(4-chlorophenyl)thiazol-2-yl)hydrazone

CAS Number: 357649-93-5
Empirical Formula (Hill Notation): C₁₄H₁₄ClN₃S
Molecular Weight: 291.80
MDL Number: MFCD02307488
Linear Formula: C₁₄H₁₄ClN₃S
Product Type: Chemical

CAS NO: 1345847-93-9Angiotensin-converting Enzyme (ACE) inhibitors
Assay: ≥98% (HPLC)
color
white to beige
Form: powder
InChI Key
YYTHPXHGWSAKIZ-UHFFFAOYSA-N
solubility
DMSO: >10 mg/mL
Storage temp.: 2-8°C
Biochem/physiol Actions:
CPTH2 is a histone acetyltransferase (HAT) inhibitor modulating the Gcn5 network. Histone Acetyltransferase (HAT) inhibitor modulating Gcn5 network. Histone acetyltransferases (HATs) act as transcriptional coactivators. Histone acetylation plays an important role in regulating the chromatin structure and is tightly regulated by two classes of enzyme, histone acetyltransferases (HAT) and histone deacetylases (HDAC). Deregulated HAT and HDAC activity plays a role in the development of a range of cancers. Consequently, inhibitors of these enzymes have potential as anticancer agents.
Features and Benefits:
This compound is a featured product for Gene Regulation research. Click here to discover more featured Gene Regulation products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
RIDADR: NONH for all modes of transport
WGK Germany: nwg
Purity: ≥98% (HPLC)
Storage Temp.: 2-8°C
UNSPSC
12352200
PubMed ID:http://jpet.aspetjournals.org/content/97/1/48