Cephradine

Product Name: Cephradine

Synonym: Cefradin

CAS Number: 38821-53-3
Empirical Formula (Hill Notation): C₁₆H₁₉N₃O₄S
Molecular Weight: 349.40
MDL Number: MFCD00865048
Linear Formula: C₁₆H₁₉N₃O₄S
Product Type: Chemical

CAS NO: 58546-56-8TGF-beta_Smad inhibitors
antibiotic activity spectrum
Gram-negative bacteria

Gram-positive bacteria
Form: powder
InChI Key
RDLPVSKMFDYCOR-UEKVPHQBSA-N
Mode of action
cell wall synthesis | interferes
solubility
1 M NH4OH: soluble50 mg/mL
Storage temp.: 2-8°C
Application: Cefradin was used to study the effect of expression, binding, and inhibition of PBP3 and other penicillin-binding proteins (PBPs) on bacterial cell wall mucopeptide synthesis.
Biochem/physiol Actions:
Cefradin is a semi-synthetic cephalosporin that inhibits the last stage of bacterial cell wall synthesis by binding to certain penicillin-binding proteins (PBPs), such as PBP3, which results in cell lysis. Cell lysis is mediated by bacterial cell wall autolytic enzymes. It is effective against Gram-positive and Gram-negative bacteria. Cefradin may also interfere with autolysin inhibitors.
Other Notes:
Keep container tightly closed in a dry and well-ventilated place.
Symbol
GHS07, GHS08
Signal word
Danger
Hazard statements
H315-H317-H319-H334-H335
Precautionary statements
P261-P280-P305 + P351 + P338-P342 + P311
Hazard Codes
Xn
Risk Statements
36/37/38-42/43
Safety Statements
22-26-36/37-45
RIDADR: NONH for all modes of transport
WGK Germany: 2
Storage Temp.: 2-8°C
UNSPSC
51101500
PubMed ID:http://jpet.aspetjournals.org/content/93/3/305