Product Name: Monoclonal Anti-Cytohesin-1 antibody produced in mouse
MDL Number: MFCD03457552
Product Type: Chemical
CAS NO: DNA-PK inhibitors
antibody Form: purified immunoglobulin
application(s)
immunocytochemistry: suitable
indirect ELISA: suitable
microarray: suitable
western blot: 2-4 μg/mL using a whole extract of cultured human lymphoma Raji cells
biological source
mouse
clone
CYT1-82, monoclonal
Concentration: ~2 mg/mL
Conjugate: unconjugated
Form: buffered aqueous solution
isotype
IgG1
Mol wt: antigen mol wt ~50 kDa
Shipped in: dry ice
species reactivity
human
Storage temp.: −20°C
Application: Monoclonal Cytohesin-1 antibody is suitable for:
•Western blot at a cocentration of 2-4μg/mL using a whole extract of cultured human lymphoma Raji cells
•Immunocytochemistry
•Indirect ELISA
•Microarray
Biochem/physiol Actions:
Cytohesin-1 is an important factor in vesicular protein trafficking and coatamer assembly in the cell. It also promotes cellular adhesion via binding to the β2 integrin cytoplasmic domain.
Features and Benefits:
Antibody Bioguarantee
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General description: Cytohesin-1 is a 47kDa protein of B2-1 gene. It is highly expressed in immune cells and is predominantly found in natural killer cells and peripheral T lymphocytes. Its expression has also been reported in purified monocytes and several cultured cell lines. Cytohesin-1 contains two structural motifs: a large central Sec7 domain (200 amino acids) and a carboxy-terminal PH domain (100 amino acids).
Immunogen:
recombinant human cytohesin-1.
Physical Form: Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.
WGK Germany: –
Storage Temp.: −20°C
UNSPSC
12352203
PubMed ID:http://jpet.aspetjournals.org/content/95/1/1