Name : Recombinant Human DKK-1 Protein (His Tag), HPLC-verified Biological Activity : Background : Dickkopf (DKK) family proteins, consisting of DKK-1, DKK-2, DKK-3 and DKK-4, function as secreted Wnt antagonists by inhibiting Wnt coreceptors LRP5/6. DKK-1, DKK-2, and DKK-4 also bind cell surface Kremen-1 or Kremen-2 and promote the internalization of LRP5/6. Dickkopf related protein …
Continue reading “Recombinant Human DKK-1 Protein (His Tag), HPLC-verified”
Name : Recombinant Human DKK-1 Protein (hFc Tag) Biological Activity : Background : Dickkopf (DKK) family proteins, consisting of DKK-1, DKK-2, DKK-3 and DKK-4, function as secreted Wnt antagonists by inhibiting Wnt coreceptors LRP5/6. DKK-1, DKK-2, and DKK-4 also bind cell surface Kremen-1 or Kremen-2 and promote the internalization of LRP5/6. Dickkopf related protein 1 …
Continue reading “Recombinant Human DKK-1 Protein (hFc Tag)”
Name : Recombinant Human DHRS9 Protein (His Tag) Biological Activity : Background : Dehydrogenase/reductase (SDR family) member 9 (DHRS9) is aberrantly expressed in colorectal cancer (CRC), the decreased expression of DHRS9 correlates with tumor progression and may serve as a potential prognostic biomarker in CRC. The human regulatory macrophage (Mreg) has emerged as a promising …
Continue reading “Recombinant Human DHRS9 Protein (His Tag)”
Name : Recombinant Human Desmoglein-2 Protein (His Tag), HPLC-verified Biological Activity : Background : Desmoglein-2 (DSG2) is a specific cadherin of the cell-cell contact in cardiac desmosomes. Mutations in the DSG2-gene are regarded to cause arrhythmogenic (right ventricular) cardiomyopathy (ARVC) which is a rare but severe heart muscle disease. The depletion of DSG2 markedly decreased …
Continue reading “Recombinant Human Desmoglein-2 Protein (His Tag), HPLC-verified”
Name : Recombinant Human Desmocollin 2/DSC2 Protein (His Tag), HPLC-verified Biological Activity : Background : DSC2 is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. Like other desmocollins, murine DSC2 has two products, Dsc2a and Dsc2b, produced by alternative splicing of a 46 bp exon which encodes 11 …
Continue reading “Recombinant Human Desmocollin 2/DSC2 Protein (His Tag), HPLC-verified”
Name : Recombinant Human Desmocollin 2/DSC2 Protein (His Tag) Biological Activity : Background : DSC2 is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. Like other desmocollins, murine DSC2 has two products, Dsc2a and Dsc2b, produced by alternative splicing of a 46 bp exon which encodes 11 COOH-terminal …
Continue reading “Recombinant Human Desmocollin 2/DSC2 Protein (His Tag)”
Name : Recombinant Human Dermcidin Protein (hFc Tag) Biological Activity : Background : Hepatocellular carcinoma (HCC) is a major contributor to cancer-related deaths due to its often late stage diagnosis, and dermcidin (DCD) may have the potential to be used as a serum biomarker for HCC for more timely diagnoses. Human dermcidin (DCD) is an antimicrobial peptide …
Continue reading “Recombinant Human Dermcidin Protein (hFc Tag)”
Name : Recombinant Canine IL-11RA/IL-11R alpha Protein (hFc Tag) Biological Activity : Background : Interleukin 11 receptor, alpha subunit (IL11RA/IL-11RA) is a subunit of the interleukin 11 receptor which is a member of the hematopoietic cytokine receptor family. IL11RA/IL-11RA is expressed in some cell lines, including the myelogenous leukemia cell line K562, the megakaryocytic leukemia …
Continue reading “Recombinant Canine IL-11RA/IL-11R alpha Protein (hFc Tag)”
Name : Recombinant Human DEP-1 Protein (aa 997-1337, His Tag) Biological Activity : Background : DEP1 / PTPRJ (Receptor-type tyrosine-protein phosphatase eta) is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes, including cell growth, differentiation, mitotic cycle, and oncogenic transformation. …
Continue reading “Recombinant Human DEP-1 Protein (aa 997-1337, His Tag)”
Name : Recombinant Human Defensin alpha 3/DEFA3 Protein (hFc Tag) Biological Activity : Background : Biological Activity : Testing in progress Expression Host : Human Source : HEK293 Cells Tag : Protein Accession No. : NP_005208.1 NCBI Gene ID : Synonyms : Synonyms : defensin alpha 3 Amino Acid Sequence : Molecular Weight : The …
Continue reading “Recombinant Human Defensin alpha 3/DEFA3 Protein (hFc Tag)”