Recombinant Human PPT1 Protein (hFc Tag)

Name : Recombinant Human PPT1 Protein (hFc Tag) Biological Activity : Background : Mutations in the depalmitoylating enzyme gene, PPT1, cause the infantile form of Neuronal Ceroid Lipofuscinosis (NCL), an early onset neurodegenerative disease. Mutations in palmitoyl protein thioesterase-1 (PPT1) have been found to cause the infantile form of neuronal ceroid lipofuscinosis, which is a …

Recombinant Human PPM1G Protein (aa 317-546, His Tag)

Name : Recombinant Human PPM1G Protein (aa 317-546, His Tag) Biological Activity : Background : Protein phosphatase 1G, also known as Protein phosphatase 1C, Protein phosphatase 2C isoform gamma, Protein phosphatase magnesium-dependent 1 gamma, PP2C-gamma, PPM1G and PPM1C, is a cytoplasm protein that belongs to the PP2C family. PPM1G / PP2C-gamma is widely expressed. It …

Recombinant Cynomolgus, Rhesus CD47 Protein (ECD, His Tag), HPLC-verified

Name : Recombinant Cynomolgus, Rhesus CD47 Protein (ECD, His Tag), HPLC-verified Biological Activity : Background : CD47 contains 1 Ig-like V-type (immunoglobulin-like) domain and is a receptor for the C-terminal cell binding domain of thrombospondin. It may play a role in membrane transport and signal transduction. CD47 is also a membrane protein, which is involved …

Recombinant Human PPM1A Protein (His Tag)

Name : Recombinant Human PPM1A Protein (His Tag) Biological Activity : Background : Protein phosphatase 1A (PPM1A / PP2CA) is an enzyme belonging to the PP2C family of Ser / Thr protein phosphatases. Members of PP2C family are negative regulators of cell stress response pathways and the MAP kinases and MAP kinase kinases. It has …

Recombinant Human PPIL2 Protein (aa 280-457, His Tag)

Name : Recombinant Human PPIL2 Protein (aa 280-457, His Tag) Biological Activity : Background : PPIL2, is an enzyme that belongs to the cyclophilin family. The cyclophilins are peptidylprolyl isomerases and are highly conserved ubiquitous. They play an important role in protein folding, immunosuppression by cyclosporin A, and infection of HIV-1 virions. PPIL2 interacts with …

Recombinant Human PPIL1 Protein (His Tag)

Name : Recombinant Human PPIL1 Protein (His Tag) Biological Activity : Background : PPIL1 is a member of the cyclophilin family. Cyclophilins are well conserved and ubiquitous. Members of cyclophilin family take a significant part in protein folding, immunosuppression by cyclosporin A, and infection of HIV-1 virions. PPIL1 is a peptidylprolyl isomerase(PPIase). It increases the …

Recombinant Human PPCDC Protein (His Tag)

Name : Recombinant Human PPCDC Protein (His Tag) Biological Activity : Background : PPC-DC, also known as PPCDC, belongs to the HFCD (homo oligomeric flavin containing Cys decarboxylase) superfamily which takes a part in the biosynthesis of coenzyme A (CoA) from pantothenate (Vitamin B). Biosynthesis of coenzyme A (CoA) from pantothenic acid (vitamin B5) is …

Recombinant Human PPAR alpha /NR1C1 Protein (His Tag)

Name : Recombinant Human PPAR alpha /NR1C1 Protein (His Tag) Biological Activity : Background : Peroxisome proliferators include hypolipidemic drugs, herbicides, leukotriene antagonists, and plasticizers; this term arises because they induce an increase in the size and number of peroxisomes. Peroxisomes are subcellular organelles found in plants and animals that contain enzymes for respiration and …

Recombinant Human PPAR gamma /NR1C3 Protein (His & GST Tag)

Name : Recombinant Human PPAR gamma /NR1C3 Protein (His & GST Tag) Biological Activity : Background : Peroxisome proliferator-activated receptor gamma (PPARG), a nuclear hormone receptor, plays a critical role in the lipid and glucose homeostasis, adipocyte differentiation, as well as intracellular insulin-signaling events. The peroxisome proliferator-activated receptor gamma (PPARgamma) regulates osteoblast and osteoclast differentiation, …

Recombinant Human PON3 Protein (50 Ser/Asn, His Tag)

Name : Recombinant Human PON3 Protein (50 Ser/Asn, His Tag) Biological Activity : Background : PON3 was enriched in the mitochondria-associated membrane fraction of hepatocytes. PON3 deficiency resulted in impaired mitochondrial respiration, increased mitochondrial superoxide levels, and increased hepatic expression of inflammatory genes. PON3 deficiency did not influence atherosclerosis development on an apolipoprotein E null …