Borussertib, a Covalent-Allosteric Akt Inhibitor

Protein kinases inhibition is a common therapeutic strategy for many diseases, including cancers, inflammatory diseases, diabetes and neurodegenerative disorders. The Ser-/Thr-specific kinaseĀ AktĀ is also known as protein kinase B. It plays a key role in PKBPI3K/Akt/mTOR-pathway. Alterations and disorders in the PI3K/Akt signaling pathway relate to different types of solid tumors such as lung cancer, and …

anti-ROR1 antibody, Systimmune

Product Name : ROR1Target points: Sichuan BailiSystimmuneStatus: Organization : ProteinShort name : Homo sapiensType: Organism: Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both …

Recombinant Human Syntaxin 7 Protein (His Tag)

Name : Recombinant Human Syntaxin 7 Protein (His Tag) Biological Activity : Background : Biological Activity : Testing in progress Expression Host : Human Source : HEK293 Cells Tag : Protein Accession No. : O15400-1 NCBI Gene ID : Synonyms : Synonyms : syntaxin 7 Amino Acid Sequence : Molecular Weight : The recombinant human …

Recombinant Human Syntaxin 7 Protein (mFc Tag)

Name : Recombinant Human Syntaxin 7 Protein (mFc Tag) Biological Activity : Background : Biological Activity : Testing in progress Expression Host : Human Source : HEK293 Cells Tag : Protein Accession No. : NP_003560.2 NCBI Gene ID : Synonyms : Synonyms : syntaxin 7 Amino Acid Sequence : Molecular Weight : The recombinant human …

Recombinant Human Syntaxin 3 Protein (His Tag)

Name : Recombinant Human Syntaxin 3 Protein (His Tag) Biological Activity : Background : STX3, also known as syntaxin 3, belongs to the syntaxin family. STX3 is a target membrane protein (t-SNARE) that is needed for membrane fusion. Membrane fusion requires the formation of a complex between a vesicle protein (v-SNARE) and t-SNAREs. STX3, together …

Recombinant Human Syndecan-4 Protein (His Tag)

Name : Recombinant Human Syndecan-4 Protein (His Tag) Biological Activity : Background : SDC4 (Syndecan-4), also known as Syn4, is a transmembrane heparan sulfate proteoglycan that co-operates with integrins during cell-matrix interactions for the assembly of focal adhesions and actin stress fibers and in the phosphorylation of focal adhesion kinase (FAK) on Tyr397. Syndecan-4 plays …

Recombinant Human Syndecan-3 Protein (ECD, His Tag)

Name : Recombinant Human Syndecan-3 Protein (ECD, His Tag) Biological Activity : Background : Biological Activity : Testing in progress Expression Host : Human Source : HEK293 Cells Tag : Protein Accession No. : ABM82826.1 NCBI Gene ID : Synonyms : Synonyms : syndecan 3 Amino Acid Sequence : Molecular Weight : The recombinant human …

Recombinant Human Syndecan-2/CD362 Protein (ECD, His Tag)

Name : Recombinant Human Syndecan-2/CD362 Protein (ECD, His Tag) Biological Activity : Background : The key players in the miR-20a-5p/SDC2 axis may be a potential diagnostic biomarker and therapeutic target for OS patients. SDC2 methylation as a blood-based DNA test for early detection of colorectal cancer (CRC). Biological Activity : Testing in progress Expression Host …

Recombinant Human Syndecan-1/CD138 Protein (ECD, His & AVI Tag), Biotinylated

Name : Recombinant Human Syndecan-1/CD138 Protein (ECD, His & AVI Tag), Biotinylated Biological Activity : Background : Syndecan-1 also known as SDC1 and CD138, is the most extensively studied member of the syndecan family. It is found mainly in epithelial cells, but its expression is developmentally regulated during embryonic development. Syndecan-1/SDC1/CD138 has been shown to …

Recombinant Human Syndecan-1/CD138 Protein (ECD, His Tag), HPLC-verified

Name : Recombinant Human Syndecan-1/CD138 Protein (ECD, His Tag), HPLC-verified Biological Activity : Background : Syndecan-1 also known as SDC1 and CD138, is the most extensively studied member of the syndecan family. It is found mainly in epithelial cells, but its expression is developmentally regulated during embryonic development. Syndecan-1/SDC1/CD138 has been shown to mediate cell …