Protein kinases inhibition is a common therapeutic strategy for many diseases, including cancers, inflammatory diseases, diabetes and neurodegenerative disorders. The Ser-/Thr-specific kinaseĀ AktĀ is also known as protein kinase B. It plays a key role in PKBPI3K/Akt/mTOR-pathway. Alterations and disorders in the PI3K/Akt signaling pathway relate to different types of solid tumors such as lung cancer, and …
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