Product Name: Anti-CDC23 (286-300) antibody produced in rabbit
Synonym: Anti-APC8; Anti-Cell division cycle protein 23
Product Type: Chemical
CAS NO: 496807-64-8Inflammation/Immunology inhibitors
antibody Form: IgG fraction of antiserum
application(s)
western blot: 1:500-1:2,000
biological source
rabbit
clone
polyclonal
Conjugate: unconjugated
Form: buffered aqueous solution
Mol wt: antigen mol wt ~69 kDa
Shipped in: dry ice
species reactivity
human
Storage temp.: −20°C
Application: Anti-CDC23 (286-300) antibody is suitable for western blot analysis at a dilution of 1:500-1:2,000.
Yale Center for High Throughput Cell Biology IF-tested antibodies. Each antibody is tested by immunofluorescence against HUVEC cells using the Yale HTCB IF protocol. To learn more about the Sigma Life Science and Yale Center for High Throughput Cell Biology partnership, visit sigma.com/htcb-if.
Biochem/physiol Actions:
CDC23 is responsible for controlling cell cycle progression through mitosis and the G1 phase. It is also involved in the pathogenesis of myeloid leukemias characterized by abnormalities of chromosome 5.
Features and Benefits:
Antibody Bioguarantee
Evaluate our antibodies with complete peace of mind. If the antibody does not perForm in your application, we will issue a full credit or replacement antibody. Learn more.
General description: CDC23, a TPR protein component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase. The gene contains 16 exons and spans approximately 31 kb with molecular mass of 68,293 Da.
Immunogen:
synthetic peptide corresponding to amino acids 286-300 of human CDC23
Physical Form: Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.
Storage Temp.: −20°C
UNSPSC
12352203
PubMed ID:http://jpet.aspetjournals.org/content/93/3/407