Product Name: Cathepsin B from human liver
Synonym: Cathepsin B1
CAS Number: 9047-22-7
MDL Number: MFCD00130748
Product Type: Chemical
CAS NO: 23031-32-5Epigenetics_Compound_Library inhibitors
Form: buffered aqueous solution
Shipped in: dry ice
Storage temp.: −70°C
Biochem/physiol Actions:
Cathepsin B has been found to cleave procaspase 1 and procaspase 11 and to induce apoptosis in digitonin-permeabilized cells. Translocation of cathepsin B from the cytoplasm to the nucleus contributes to bile salt induced apoptosis of rat hepatocytes. Levels of cathepsin B in PC12 cells significantly decrease 12 to 24 hours after apoptosis is induced.
Packaging:
Package size based on protein content
Physical Form: Solution in 50 mM sodium acetate, pH 5.0, with 1 mM EDTA.
Unit Definition:
One unit will liberate 1 nanomole of 7-amino-4-methylcoumarin from Z-Arg-Arg 7-amido-4-methylcoumarin per min at pH 6.0 at 40 °C.
RIDADR: NONH for all modes of transport
WGK Germany: 3
Storage Temp.: −70°C
Enzyme Commission (EC) Number
3.4.22.1(BRENDA|IUBMB)
UNSPSC
12352200
PubMed ID:http://jpet.aspetjournals.org/content/93/3/470