CL-82198

Product Name: CL-82198

Synonym: N-[4-(4-Morpholinyl)butyl]–2-benzofurancarboxamide

CAS Number: 307002-71-7
Empirical Formula (Hill Notation): C₁₇H₂₂N₂O₃
Molecular Weight: 302.37
MDL Number: MFCD12828877
Linear Formula: C₁₇H₂₂N₂O₃
Product Type: Chemical

CAS NO: 1261079-38-2IRAK inhibitors
Assay: ≥98% (HPLC)
color
white to off-white
Form: powder
InChI Key
KUJQEQAVMNFFAO-UHFFFAOYSA-N
originator
Wyeth
solubility
DMSO: >10 mg/mL
Storage temp.: 2-8°C
Biochem/physiol Actions:
CL-82198 is a selective inhibitor of MMP-13 that displays no activity at MMP-1, MMP-9 or TACE. It is also a selective S1′ pocket binder, binding within the entire S1′ pocket of MMP-13, docking with the morpholine ring adjacent to the catalytic zinc atom without zinc chelation.
Features and Benefits:
This compound was developed by Wyeth. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
Symbol
GHS07
Signal word
Warning
Hazard statements
H302
Hazard Codes
Xn
Risk Statements
22
RIDADR: NONH for all modes of transport
WGK Germany: 3
Purity: ≥98% (HPLC)
Storage Temp.: 2-8°C
UNSPSC
12352200
PubMed ID:http://jpet.aspetjournals.org/content/96/2/151