Product Name: Creatine Kinase BB Fraction human
MDL Number: MFCD02677919
Product Type: Chemical
CAS NO: 393105-53-8Factor Xa inhibitors
Assay: ≥90% (SDS-PAGE)
Concentration: ≥1.0 mg/mL
Form: liquid
Recombinant: expressed in Pichia pastoris
Storage temp.: −70°C
Application: Human creatine kinase BB fraction has been used to investigate the survival benefit of the late percutaneous coronary intervention in patients after acute myocardial infarction. Human creatine kinase BB fraction has also been used in a study to analyze protein oxidations and resultant loss of function.
Biochem/physiol Actions:
The product is used as a control in monitoring levels in cerebrospinal fluid by ELISA. Creatine kinase (CK) BB is a member of the CK gene family and is a cytosolic CK isoForm present in the brain. The molecular mass is found to be 35-50 kDa. CKs catalyze the reversible transfer of a phosphoryl group between ATP and creatine. It plays an important role in the regulation of ATP level in neural cells. Therefore, a decrease in CK BB activity is one of the biochemical markers of the CNS cell damage in age-related neurodegenerative diseases such as Alzheimer’s disease, Pick’s disease, and Lewy body dementia.
Frequently Asked Questions:
Frequently Asked Questions are available for this Product.
General description: Solution in 50% glycerol, Tris buffer with 10 mM Bis-Tris-HCl, 0.5mM DTT, 0.5mM EDTA
Unit Definition:
One unit will transfer 1.0 μmole of phosphate from creatine phosphate to ADP per minute at 37°C (measured at 340nm as one equimolar amount of NADH produced by coupled reaction).
RIDADR: NONH for all modes of transport
WGK Germany: 2
Purity: ≥90% (SDS-PAGE)
Storage Temp.: −70°C
UNSPSC
12352204
PubMed ID:http://jpet.aspetjournals.org/content/97/2/125