Name :
Recombinant Cynomolgus COLEC10 Protein (hFc Tag)
Biological Activity :
Background :
COLEC1 is a member of the C-lectin family. Members of this family possess collagen-like sequences and carbohydrate recognition domains. The other members of this family are secreted proteins and bind to carbohydrate antigens on microorganisms facilitating their recognition and removal. This gene product is a cytosolic protein, a characteristic that suggests that it may have different biological functions than other C-lectins.
Biological Activity :
Testing in progress
Expression Host :
Cynomolgus
Source :
HEK293 Cells
Tag :
Protein Accession No. :
XP_005564031.1
NCBI Gene ID :
Synonyms :
Synonyms :
collectin sub-family member 10 (C-type lectin)
Amino Acid Sequence :
Molecular Weight :
The recombinant cynomolgus COLEC10 is a disulfide-linked homodimer. The reduced monomer comprises 425 amino acids and has a calculated molecular mass of 47.5 KDa.The apparent molecular mass of the protein is approximately 56.3 KDa in SDS-PAGE.
Purity :
> 90 % as determined by SDS-PAGE
State of Matter :
Product Concentration :
Storage and Stability :
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Endotoxin Level :
< 1.0 EU per μg of the protein as determined by the LAL method
Protein Construction :
A DNA sequence encoding the cynomolgus COLEC10 (XP_005564031.1) (Gly113-Lys277) was expressed with the Fc region of human IgG1 at the N-terminus.
Buffer Solution :
Lyophilized from sterile PBS, pH 7.4.Please contact us for any concerns or special requirements. Normally 5 % – 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hardcopy of datasheet.
Shipping :
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Redissolution :
A hardcopy of datasheet with reconstitution instructions is sent along with the products. Please refer to it for detailed information.
Synonyms :
References & Citations :
Ohtani K., et al.,(1999), Molecular cloning of a novel human collectin from liver (CL-L1). J. Biol. Chem. 274:13681-13689.Clark H.F., et al., (2003), The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.Genome Res. 13:2265-2270.Ota T., et al.,(2004), Complete sequencing and characterization of 21,243 full-length human cDNAs.Nat. Genet. 36:40-45.
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