Name :
Recombinant Human TM4SF2/TSPAN7 Protein (His Tag)
Biological Activity :
Background :
TALLA-1, also known as TSPAN7, is a member of the transmembrane 4 superfamily Most members of this family are cell-surface proteins that are characterized by the presence of four hydrophobic domains. TALLA-1 gene is associated with X-linked mental retardation and neuropsychiatric diseases such as Huntington’s chorea, fragile X syndrome and myotonic dystrophy. TALLA-1 is a cell surface glycoprotein and may have a role in the control of neurite outgrowth. It is known to complex with integrins.
Biological Activity :
Testing in progress
Expression Host :
Human
Source :
HEK293 Cells
Tag :
Protein Accession No. :
AAH18036.1
NCBI Gene ID :
Synonyms :
Synonyms :
tetraspanin 7
Amino Acid Sequence :
Molecular Weight :
The recombinant human TSPAN7 consists of 112 amino acids and predicts a molecular mass of 13 KDa. It migrates as an approximately 24-30 KDa band in SDS-PAGE under reducing conditions.
Purity :
> 95 % as determined by SDS-PAGE
State of Matter :
Product Concentration :
Storage and Stability :
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Endotoxin Level :
< 1.0 EU per μg of the protein as determined by the LAL method
Protein Construction :
A DNA sequence encoding the human TSPAN7 (AAH18036.1) (Arg113-Met213) was expressed with a polyhistidine tag at the C-terminus.
Buffer Solution :
Lyophilized from sterile PBS, pH 7.4.Please contact us for any concerns or special requirements. Normally 5 % – 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hardcopy of datasheet.
Shipping :
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Redissolution :
A hardcopy of datasheet with reconstitution instructions is sent along with the products. Please refer to it for detailed information.
Synonyms :
A15 Protein, Human; CCG-B7 Protein, Human; CD231 Protein, Human; DXS1692E Protein, Human; MRX58 Protein, Human; MXS1 Protein, Human; TALLA-1 Protein, Human; TM4SF2 Protein, Human; TM4SF2b Protein, Human TM4SF2/TSPAN7 背景信息 TALLA-1, also known as TSPAN7, is a member of the transmembrane 4 superfamily Most members of this family are cell-surface proteins that are characterized by the presence of four hydrophobic domains. TALLA-1 gene is associated with X-linked mental retardation and neuropsychiatric diseases such as Huntington’s chorea, fragile X syndrome and myotonic dystrophy. TALLA-1 is a cell surface glycoprotein and may have a role in the control of neurite outgrowth. It is known to complex with integrins.
References & Citations :
Berditchevski F. 2002, J Cell Sci. 114 (23): 4143-51. Castellví-Bel S. et al., 2001, Mol Genet Metab. 72 (2): 104-8. Abidi FE. et al., 2002, J Med Genet. 39 (6): 430-3.
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