ADL-5859

Product Name : ADL-5859Description:ADL5859 is a potent, orally bioavailable delta opioid receptor agonist for the treatment of pain ( Ki of 0.8 nM ). ADL5859 agonizes δ-opioid receptor with a 1000-fold selectivity than µ- or κ-opioid receptor with Ki of 32 nM and 37 nM, respectively.CAS: 850173-95-4Molecular Weight:428.95Formula: C24H29ClN2O3Chemical Name: N,N-diethyl-4-5-hydroxyspiro[chromene-2,4′-piperidin]-4-ylbenzamide hydrochlorideSmiles : Cl.SGI-1776 JAK/STAT …

Recombinant Human PSG6 Protein (His Tag)

Name : Recombinant Human PSG6 Protein (His Tag) Biological Activity : Background : PSG6 is a pregnancy-specific glycoprotein(PSG). PSGs are secreted proteins produced by the rodent and primate placenta and play a critical role in pregnancy success. The levels of PSGs are highest during the third trimester of pregnancy, a time marked by the most …

Recombinant Human PSG1 Protein (His Tag)

Name : Recombinant Human PSG1 Protein (His Tag) Biological Activity : Background : Pregnancy-specific glycoproteins (PSGs) are a family of Ig-like proteins secreted by specialized placental cells. The PSG1 structure is composed of a single Ig variable region-like N-terminal domain and three Ig constant region-like domains termed A1, A2, and B2. Members of the human …

Recombinant Human PSG1 Protein (hFc Tag)

Name : Recombinant Human PSG1 Protein (hFc Tag) Biological Activity : Background : Pregnancy-specific glycoproteins (PSGs) are a family of Ig-like proteins secreted by specialized placental cells. The PSG1 structure is composed of a single Ig variable region-like N-terminal domain and three Ig constant region-like domains termed A1, A2, and B2. Members of the human …

Recombinant Human PSAP/Prosaposin Protein (His Tag)

Name : Recombinant Human PSAP/Prosaposin Protein (His Tag) Biological Activity : Background : Prosaposin (PSAP) gene mutations, affecting saposin B (Sap-B) domain, cause a rare metachromatic leukodystrophy (MLD) variant in which arylsulfatase A (ARSA) activity is normal. The human prosaposin gene (PSAP) was previously localized to 10q21–>q22 by isotopic in situ hybridization using a human …

Recombinant Human Proteinase 3 Protein (203S/A, His Tag)

Name : Recombinant Human Proteinase 3 Protein (203S/A, His Tag) Biological Activity : Background : Biological Activity : Testing in progress Expression Host : Human Source : HEK293 Cells Tag : Protein Accession No. : NP_002768.3 NCBI Gene ID : Synonyms : Synonyms : proteinase 3 Amino Acid Sequence : Molecular Weight : The recombinant …

Recombinant Human PRTFDC1 Protein (His Tag)

Name : Recombinant Human PRTFDC1 Protein (His Tag) Biological Activity : Background : PRTFDC1 is a member of the purine/pyrimidine phosphoribosyltransferase family. It can bind GMP, IMP and alpha-D-5-phosphoribosyl 1-pyrophosphate (PRPP). The epigenetic silencing of PRTFDC1 by hypermethylation of the CpG island leads to a loss of PRTFDC1 function, which might be involved in squamous …

Recombinant Human Trypsin-3/PRSS3 Protein (His Tag)

Name : Recombinant Human Trypsin-3/PRSS3 Protein (His Tag) Biological Activity : Background : Trypsin-3, also known as Trypsin III, brain trypsinogen, Serine protease 3 and PRSS3, is a secreted protein that belongs to the peptidase S1 family. Trypsin-3 / PRSS3 is expressed is in pancreas and brain. It contains one peptidase S1 domain. Trypsin-3 / …

Recombinant Human PRRG2 Protein (mFc Tag)

Name : Recombinant Human PRRG2 Protein (mFc Tag) Biological Activity : Background : The genes encoding a family of proteins termed proline-rich gamma-carboxyglutamic acid (PRRG) proteins were identified and characterized more than a decade ago. These novel membrane proteins have an extracellular gamma-carboxyglutamic acid (Gla) protein domain and cytosolic WW binding motifs. Several of the …

Recombinant Human PRPS2 Protein (His Tag)

Name : Recombinant Human PRPS2 Protein (His Tag) Biological Activity : Background : PRPS2, a subset of PRS, is reported to be a potential protein associated with Sertoli-cell only syndrome. PRPS2 expression correlates with Sertoli-cell only syndrome and inhibits the apoptosis of TM4 Sertoli cells via the p53/Bcl-2/caspases signaling pathway. The gene for PRS II …