Ficial effects. Numerous studies have demonstrated that gut microbiota can cleave the C-ring of tea catechins to generate several lower molecular weight phenolic acids as well as ring-fission metabolites, such as 4-hydroxylphenylacetic acid, 3-(3-hydroxyphenyl)-propionic acid, 5-(39,49-dihydroxyphenyl)-c-valerolactone, and 5(39,49,59-trihydroxyphenyl)-c-valerolactone [4,22,37]. With the unique benzotropolone structure, it is unlikely that theaflavins can be metabolized to similar simple …
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