Recombinant Cynomolgus CD52 Protein (hFc Tag)

Name : Recombinant Cynomolgus CD52 Protein (hFc Tag) Biological Activity : Background : CD52 / CDW52 is a small glycosylphosphatidylinositol (GPI) anchored glycoprotein. It has a mature peptide comprising only 12 amino acids and is abundantly expressed on human lymphocytes. From the clinical point of view this protein is an important target for therapeutic interventions …

Recombinant Human PRELP Protein (mFc Tag)

Name : Recombinant Human PRELP Protein (mFc Tag) Biological Activity : Background : PRELP (proline/arginine-rich end leucine-rich repeat protein) is a member of the leucine-rich repeat (LRR) family of extracellular matrix proteins in connective tissue. In contrast with other members of the family, the N-terminal domain of PRELP has a high content of proline and …

Recombinant Human PRC1 Protein (His Tag)

Name : Recombinant Human PRC1 Protein (His Tag) Biological Activity : Background : PRC1 (protein regulator of cytokinesis 1) is a key regulator of cytokinesis that cross-links antiparrallel microtubules at an average distance of 35 nM. It is essential for controlling the spatiotemporal formation of the midzone and successful cytokinesis. PRC1 is required for KIF14 …

Recombinant Human PRAP1 Protein (His Tag)

Name : Recombinant Human PRAP1 Protein (His Tag) Biological Activity : Background : PRAP1 is a protein interacting partner of MAD1 and that PRAP1 is able to down-regulate MAD1 and suppress mitotic checkpoint signalling in HCC. PRAP1 is a novel p53 target gene. The induction of PRAP1 expression by p53 may promote resistance of cancer …

Recombinant Human PRAP1 Protein (mFc Tag)

Name : Recombinant Human PRAP1 Protein (mFc Tag) Biological Activity : Background : PRAP1 is a protein interacting partner of MAD1 and that PRAP1 is able to down-regulate MAD1 and suppress mitotic checkpoint signalling in HCC. PRAP1 is a novel p53 target gene. The induction of PRAP1 expression by p53 may promote resistance of cancer …

Recombinant Human PRAK/MAPKAPK5 Protein (His & GST Tag)

Name : Recombinant Human PRAK/MAPKAPK5 Protein (His & GST Tag) Biological Activity : Background : MAPKAPK5 contains 1 protein kinase domain and belongs to the protein kinase superfamily, CAMK Ser/Thr protein kinase family. MAPKAPK5 has significant sequence homology to mitogen-activated protein kinase (MAPK)-activated protein kinase (MAPKAPK). It is widely distributed. MAPKAPK5 can be phosphorylated by …

Recombinant Human PRAC Protein (His & SUMO Tag)

Name : Recombinant Human PRAC Protein (His & SUMO Tag) Biological Activity : Background : Biological Activity : Testing in progress Expression Host : Human Source : E. coli Tag : Protein Accession No. : NP_115767.1 NCBI Gene ID : Synonyms : Synonyms : Amino Acid Sequence : Molecular Weight : The recombinant human PRAC …

Recombinant Human PR-Set7 Protein

Name : Recombinant Human PR-Set7 Protein Biological Activity : Background : KMT5A (known as PR-Set7/9, SETD8 and SET8), a member of the SET domain containing methyltransferase family specifically targeting H4K20 for methylation, has been implicated in multiple biological processes. Inhibition of KMT5A attenuated proliferation and induced apoptosis. Elevated KMT5A expression was significantly correlated with extrathyroidal …

Recombinant Human PPT1 Protein (His Tag)

Name : Recombinant Human PPT1 Protein (His Tag) Biological Activity : Background : Mutations in the depalmitoylating enzyme gene, PPT1, cause the infantile form of Neuronal Ceroid Lipofuscinosis (NCL), an early onset neurodegenerative disease. Mutations in palmitoyl protein thioesterase-1 (PPT1) have been found to cause the infantile form of neuronal ceroid lipofuscinosis, which is a …

5T4 Monoclonal Antibody (524731)

Product Name : 5T4 Monoclonal Antibody (524731)Species Reactivity: HumanHost/Isotype : Mouse / IgG1Class:MonoclonalType : AntibodyClone: 524731Conjugate : UnconjugatedForm: LyophilizedConcentration : 0.5 mg/mLPurification : Protein A/GStorage buffer: PBS with 5% trehaloseContains : No PreservativeStorage conditions: -20° C, Avoid Freeze/Thaw CyclesRRID: AB_2607907Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two …