J, Frayn KN, Baak M, et al. Impact of beta-adrenergic stimulation on whole-body and abdominal subcutaneous 44. 45. 46. 47. 48. 49. 50. 51. 52. 53. 54. 55. 56. 57. 58. 59. 60. 61. adipose tissue lipolysis in lean and obese men. Diabetologia 51: 320327. doi:10.1007/s00125-007-0866-y. Sandvei M, Jeppesen PB, Sten L, Litleskare S, Johansen E, et al. Sprint interval running increases insulin sensitivity in young healthy subjects. Arch Physiol Biochem 118: 139147. doi:ten.3109/13813455.2012.677454. Gibala MJ, Tiny JP, van Essen M, Wilkin GP, Burgomaster KA, et al. Short-term sprint interval versus conventional endurance instruction: MedChemExpress Teriparatide Related initial adaptations in human skeletal muscle and physical exercise efficiency. J Physiol 575: 901911. doi:10.1113/jphysiol.2006.112094. Macpherson RE, Hazell TJ, Oliver TD, Paterson DH, Lemon PW Run sprint interval education improves aerobic performance but not maximal cardiac output. Medicine & Science in Sports & Physical exercise 43: 115122. Burgomaster KA, Howarth KR, Phillips SM, Rakobowchuk M, MacDonald MJ, et al. Similar metabolic adaptations during exercise after low volume sprint interval and regular endurance coaching in humans. J Physiol 586: 151160. doi:10.1113/jphysiol.2007.142109. Stuckey MI, Tordi N, Mourot L, Gurr LJ, Rakobowchuk M, et al. Autonomic recovery following sprint interval workout. Scand J Med Sci Sports 22: 756763. doi:10.1111/j.1600-0838.2011.01320.x. Pekkala S, Wiklund P, Hulmi JJ, Ahtiainen JP, Horttanainen M, et al. Are Skeletal Muscle FNDC5 Gene Expression and Irisin Release Regulated by Workout and Connected to Health J Physiol. doi:ten.1113/jphysiol. 2013.263707. Fain JN, Booth FW, Laughlin MH, Padilla J, Jenkins NT Exercising training does not increase muscle FNDC5 protein or mRNA expression in pigs. Metabolism epub ahead of print. Sanchez J, Nozhenko Y, Palou A, 57773-65-6 Rodriguez AM Free fatty acid effects on myokine production in combination with exercise mimetics. Mol Nutr Food Res 00: 112. Hecht R, Li YS, Sun J, Belouski E, Hall M, et al. PLOS ONE: RationaleBased Engineering of a Potent Long-Acting FGF21 Analog for the Treatment of Type 2 Diabetes. PLoS ONE. Kurosu H, Choi M, Ogawa Y, Dickson AS, Goetz R, et al. Tissue-specific Expression of betaKlotho and Fibroblast Growth Factor Receptor Isoforms Determines Metabolic Activity of FGF19 and FGF21. J Biol Chem 282: 2668726695. doi:ten.1074/jbc.M704165200. Kurosu H, Kuro-o M The Klotho gene family as a regulator of endocrine fibroblast growth factors. Molecular and Cellular Endocrinology 299: 7278. doi:ten.1016/j.mce.2008.ten.052. Fletcher JA, Meers GM, Laughlin HM, Ibdah JA, Thyfault JP, et al. Modulating fibroblast growth factor 21 in hyperphagic OLETF rats with daily physical exercise and caloric restriction. Appl Physiol Nutr Metab 37: 10541062. Hecksteden A, Wegmann M, Steffen A, Kraushaar J, Morsch A, et al. Irisin and exercising coaching in humans – Results from a randomized controlled education trial. BMC Med 11: 235. doi:10.1186/1741-7015-11-235. Norheim F, Langleite TM, Hjorth M, Holen T, Kielland A, et al. The effects of acute and chronic workout on PGC-1a, irisin and browning of subcutaneous adipose tissue in human. FEBS J. doi:ten.1111/febs.12619. Stengel A, Hofmann T, Goebel-Stengel M, Elbelt U, Kobelt P, et al. Circulating levels of irisin in patients with anorexia nervosa and different stages of obesity–correlation with body mass index. Peptides 39: 125130. doi:ten.1016/j.peptides.2012.11.014. Moreno-Navarrete JM, Ortega F, Serrano M, Guerra E,.J, Frayn KN, Baak M, et al. Effect of beta-adrenergic stimulation on whole-body and abdominal subcutaneous 44. 45. 46. 47. 48. 49. 50. 51. 52. 53. 54. 55. 56. 57. 58. 59. 60. 61. adipose tissue lipolysis in lean and obese guys. Diabetologia 51: 320327. doi:10.1007/s00125-007-0866-y. Sandvei M, Jeppesen PB, Sten L, Litleskare S, Johansen E, et al. Sprint interval running increases insulin sensitivity in young wholesome subjects. Arch Physiol Biochem 118: 139147. doi:ten.3109/13813455.2012.677454. Gibala MJ, Small JP, van Essen M, Wilkin GP, Burgomaster KA, et al. Short-term sprint interval versus traditional endurance coaching: related initial adaptations in human skeletal muscle and exercise functionality. J Physiol 575: 901911. doi:10.1113/jphysiol.2006.112094. Macpherson RE, Hazell TJ, Oliver TD, Paterson DH, Lemon PW Run sprint interval training improves aerobic efficiency but not maximal cardiac output. Medicine & Science in Sports & Exercising 43: 115122. Burgomaster KA, Howarth KR, Phillips SM, Rakobowchuk M, MacDonald MJ, et al. Related metabolic adaptations during exercise after low volume sprint interval and conventional endurance training in humans. J Physiol 586: 151160. doi:ten.1113/jphysiol.2007.142109. Stuckey MI, Tordi N, Mourot L, Gurr LJ, Rakobowchuk M, et al. Autonomic recovery following sprint interval exercise. Scand J Med Sci Sports 22: 756763. doi:10.1111/j.1600-0838.2011.01320.x. Pekkala S, Wiklund P, Hulmi JJ, Ahtiainen JP, Horttanainen M, et al. Are Skeletal Muscle FNDC5 Gene Expression and Irisin Release Regulated by Exercising and Related to Health J Physiol. doi:10.1113/jphysiol. 2013.263707. Fain JN, Booth FW, Laughlin MH, Padilla J, Jenkins NT Exercising instruction does not increase muscle FNDC5 protein or mRNA expression in pigs. Metabolism epub ahead of print. Sanchez J, Nozhenko Y, Palou A, Rodriguez AM Free fatty acid effects on myokine production in combination with workout mimetics. Mol Nutr Food Res 00: 112. Hecht R, Li YS, Sun J, Belouski E, Hall M, et al. PLOS ONE: RationaleBased Engineering of a Potent Long-Acting FGF21 Analog for the Treatment of Type 2 Diabetes. PLoS ONE. Kurosu H, Choi M, Ogawa Y, Dickson AS, Goetz R, et al. Tissue-specific Expression of betaKlotho and Fibroblast Growth Factor Receptor Isoforms Determines Metabolic Activity of FGF19 and FGF21. J Biol Chem 282: 2668726695. doi:ten.1074/jbc.M704165200. Kurosu H, Kuro-o M The Klotho gene family as a regulator of endocrine fibroblast growth factors. Molecular and Cellular Endocrinology 299: 7278. doi:ten.1016/j.mce.2008.ten.052. Fletcher JA, Meers GM, Laughlin HM, Ibdah JA, Thyfault JP, et al. Modulating fibroblast growth factor 21 in hyperphagic OLETF rats with daily physical exercise and caloric restriction. Appl Physiol Nutr Metab 37: 10541062. Hecksteden A, Wegmann M, Steffen A, Kraushaar J, Morsch A, et al. Irisin and physical exercise coaching in humans – Results from a randomized controlled training trial. BMC Med 11: 235. doi:10.1186/1741-7015-11-235. Norheim F, Langleite TM, Hjorth M, Holen T, Kielland A, et al. The effects of acute and chronic physical exercise on PGC-1a, irisin and browning of subcutaneous adipose tissue in human. FEBS J. doi:ten.1111/febs.12619. Stengel A, Hofmann T, Goebel-Stengel M, Elbelt U, Kobelt P, et al. Circulating levels of irisin in patients with anorexia nervosa and different stages of obesity–correlation with physique mass index. Peptides 39: 125130. doi:ten.1016/j.peptides.2012.11.014. Moreno-Navarrete JM, Ortega F, Serrano M, Guerra E,.

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