Product Name: Anti-CACYBP (211-225) antibody produced in rabbit
Synonym: Anti-Calcyclin binding protein isoform 1; Anti-GIG5; Anti-PNAS-107; Anti-S100A6BP; Anti-SIP
Product Type: Chemical
CAS NO: 30220-46-3NEDD8-activating Enzyme inhibitors
antibody Form: IgG fraction of antiserum
application(s)
western blot: 1:500-1:2,000
biological source
rabbit
clone
polyclonal
Conjugate: unconjugated
Form: buffered aqueous solution
Mol wt: antigen mol wt ~26 kDa
Shipped in: dry ice
species reactivity
human
Storage temp.: −20°C
Application: Anti-CACYBP (211-225) antibody is suitable for western blot analysis at a dilution of 1:500-1:2,000.
Yale Center for High Throughput Cell Biology IF-tested antibodies. Each antibody is tested by immunofluorescence against HUVEC cells using the Yale HTCB IF protocol. To learn more about the Sigma Life Science and Yale Center for High Throughput Cell Biology partnership, visit sigma.com/htcb-if.
Biochem/physiol Actions:
Anti-CACYBP (211-225) antibody act as a molecular bridge in ubiquitin E3 complexes and also participates in the ubiquitin-mediated degradation of β-catenin (CTNNB1).
General description: Calcyclin-binding protein (CacyBP) is a target protein of S100 family with molecular mass of 30 kDa. It was identified in mouse brain and Ehrlich ascites tumor (EAT) cells. It includes S100A6, S100A1, S100A12, S100B, and S100P. It is highly expressed in mouse and in rat brain, liver, spleen, and stomach, and weakly in rat lung and kidney.
Immunogen:
synthetic peptide corresponding to amino acids 211-225 of human CACYBP
Physical Form: Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.
Storage Temp.: −20°C
UNSPSC
12352203
PubMed ID:http://jpet.aspetjournals.org/content/92/4/411