Product Name: Anti-CCBP2 antibody produced in rabbit
Synonym: Anti-CCR10; Anti-CCR9; Anti-CMKBR9; Anti-Chemokine binding protein 2; Anti-D6; Anti-MGC126678; Anti-MGC138250; Anti-hD6
Product Type: Chemical
CAS NO: 803647-40-7Phosphatase_Inhibitor_Cocktail_II inhibitors
antibody Form: affinity isolated antibody
application(s)
immunohistochemistry: suitable
western blot: suitable
biological source
rabbit
clone
polyclonal
Concentration: 0.5 mg – 1 mg/mL
Conjugate: unconjugated
Form: buffered aqueous solution
Mol wt: mol wt 43 kDa
NCBI accession no.
NP_001287
Shipped in: wet ice
species reactivity
rabbit, human
Storage temp.: −20°C
Application: Rabbit Anti-CCBP2 antibody can be used for immunohistochemistry (4-8μg/ml, using paraffin-embedded tissues) and western blot (0.25μg/ml) applications.
Application: Rabbit polyclonal anti-CCBP2 is used to tag chemokine binding protein-2 for detection and quantitation by immunocytochemical and immunohistochemical (IHC) techniques. It is used as a probe to determine the presence and roles of chemokine binding protein-2 in the resolution phase of the in vivo inflammatory response via the binding/scavenging of proinflammatoy cytokines.
Features and Benefits:
Chemokine binding protein 2 (CCBP2, D6) is a β chemokine receptor expressed on lymphatic endothelial cells that binds a variety of proinflammatory cytokines to support the resolution phase of the in vivo inflammatory response. CCBP2/D6 is a chemokine-scavenging receptor that protects lymphatic surfaces from inflammatory CC-chemokines and minimizes interaction of inflammatory leukocytes with these surfaces.
General description: CCBP2 is a β chemokine receptor that may be involved in the regulation of immunological and inflammatory responses. This gene has been implicated in the lymph node metastasis of breast cancer.
Rabbit Anti-CCBP2 antibody recognizes human CCBP2.
General description: Rabbit polyclonal anti-CCBP2 reacts with human chemokine binding protein-2.
Immunogen:
The immunogen for anti-CCBP2 antibody: synthetic peptide derected towards the N terminal of human CCBP2
Physical Form: Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Sequence:
Synthetic peptide located within the following region: MAATASPQPLATEDADSENSSFYYY
RIDADR: NONH for all modes of transport
WGK Germany: 3
Storage Temp.: −20°C
UNSPSC
12352203
PubMed ID:http://jpet.aspetjournals.org/content/329/2/820