Product Name: Anti-CHRNE antibody produced in rabbit
Synonym: Anti-Cholinergic receptor, nicotinic, ε
Product Type: Chemical
CAS NO: 117928-94-6Dopamine Transporter inhibitors
antibody Form: IgG fraction of antiserum
application(s)
western blot: suitable
biological source
rabbit
clone
polyclonal
Concentration: 0.5 mg – 1 mg/mL
Conjugate: unconjugated
Form: buffered aqueous solution
Mol wt: mol wt 55 kDa
NCBI accession no.
NP_000071
Shipped in: wet ice
species reactivity
guinea pig, rat, pig, mouse
Storage temp.: −20°C
Application: Anti-CHRNE antibody produced in rabbit is suitable for western blotting at a concentration of 1.25 μg/ml.
Biochem/physiol Actions:
CHRNE is a transmembrane oligomeric ligand-gated nicotinic receptor that induces ion channel opening for the movement of positive ions when it is activated by cholinergic binding. Nicotinic acetylcholine receptors mediate presynaptic, postsynaptic and extrasynaptic signaling. Mutations in gene that codes for CHRNE results in fata; fast-channel congenital myasthenic syndrome.
Features and Benefits:
Antibody Bioguarantee
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Immunogen:
The immunogen for anti-CHRNE antibody: synthetic peptide derected towards the N terminal of human CHRNE
Physical Form: Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Sequence:
Synthetic peptide located within the following region: GLLGRGVGKNEELRLYHHLFNNYDP
RIDADR: NONH for all modes of transport
WGK Germany: 3
Storage Temp.: −20°C
UNSPSC
12352203
PubMed ID:http://jpet.aspetjournals.org/content/329/1/2