Product Name: Anti-SIRT1 antibody produced in rabbit
Synonym: Anti-Sirtuin (silent mating type information Regulation 2 homolog) 1 (S. cerevisiae)
Product Type: Chemical
CAS NO: 186097-54-1Orexin Receptor (OX Receptor) inhibitors
antibody Form: affinity isolated antibody
application(s)
western blot: suitable
biological source
rabbit
clone
polyclonal
Concentration: 0.5 mg – 1 mg/mL
Conjugate: unconjugated
Form: buffered aqueous solution
Mol wt: mol wt 82 kDa
NCBI accession no.
NP_036370
Shipped in: wet ice
species reactivity
guinea pig, rat, rabbit, human, horse, canine, mouse, pig
Storage temp.: −20°C
Application: Rabbit Anti-SIRT1 antibody can be used for western blot applications at a concentration of 0.5μg/ml.
Application: Rabbit polyclonal anti-SIRT1 antibody is used to tag sirtuin-1 for detection and quantitation by immunocytochemical and immunohistochemical (IHC) techniques. It is used as a probe to determine the presence and roles of sirtuin-1 in NAD(+) status-dependent energy homeostasis at the level of nuclear transcription control and protein deacetylation.
Features and Benefits:
Antibody Bioguarantee
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General description: Rabbit polyclonal anti-SIRT1 antibody reacts with chicken, human, mouse, rat, canine, and pig sirtuin-1 enzymes.
General description: Sirtuin (silent mating type inFormation regulation 2 homolog) 1 (S. cerevisiae) (SIRT1), a member of the NAD(+)-dependent protein deacetylase SIRT family, is involved in the regulation of nuclear transcription of genes involve in energy metabolism. SIRT1 provides a link between cellular energy status sensing (NAD(+) status) and the regulation of energy homoeostasis. SIRT1 is involved in the regulation of metabolism, cell differentiation and senescence, stress response, and cancer.
Immunogen:
The immunogen for anti-SIRT1 antibody: synthetic peptide derected towards the N terminal of human SIRT1
Physical Form: Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Sequence:
Synthetic peptide located within the following region: PETIPPPELDDMTLWQIVINILSEP
RIDADR: NONH for all modes of transport
WGK Germany: 3
Storage Temp.: −20°C
UNSPSC
12352203
PubMed ID:http://jpet.aspetjournals.org/content/331/1/96