Bendamustine hydrochloride hydrate

Product Name: Bendamustine hydrochloride hydrate

Synonym: 1H-Benzimidazole-2-butanoic acid, 5-[bis(2-chloroethyl)amino]–1-methyl monohydrochloride; Treanda

Empirical Formula (Hill Notation): C₁₆H₂₁Cl₂N₃O₂·HCl · xH₂O
Molecular Weight: 394.72 (anhydrous basis)
MDL Number: MFCD16879055
Linear Formula: C₁₆H₂₁Cl₂N₃O₂·HCl · xH₂O
Product Type: Chemical

CAS NO: 287194-40-5STING inhibitors
Assay: ≥98% (HPLC)
color
off-white
Form: powder
InChI Key
TWBJYCLUHINEDN-UHFFFAOYSA-N
originator
Teva
solubility
H2O: >30 mg/mL
Storage temp.: room temp
Biochem/physiol Actions:
Bendamustine hydrochloride is a DNA-alkylator with a distinct pattern of activity. Bendamustine activates DNA-damage stress response and apoptosis; inhibits mitotic checkpoints; and induces mitotic catastrophe.
Features and Benefits:
This compound is a featured product for Apoptosis research. Click here to discover more featured Apoptosis products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
Features and Benefits:
This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®1280), a biologically annotated collection of high-quality, ready-to-screen compounds. Click here to learn more.
Features and Benefits:
This compound was developed by Teva. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
Legal InFormation: LOPAC is a registered trademark of Sigma-Aldrich Co. LLC
Symbol
GHS06, GHS08
Signal word
Danger
Hazard statements
H301-H351-H360
Precautionary statements
P201-P281-P301 + P310-P308 + P313
Hazard Codes
T,Xn
Risk Statements
60-61-22-40
Safety Statements
36-37
RIDADR: UN 2811 6.1 / PGIII
WGK Germany: 3
RTECS
DE1590000
Purity: ≥98% (HPLC)
Storage Temp.: room temp
UNSPSC
12352200
PubMed ID:http://jpet.aspetjournals.org/content/58/3/332