CAMK1, active, GST tagged from mouse

Product Name: CAMK1, active, GST tagged from mouse

Synonym: A15051 05; D6Ertd263e

Product Type: Chemical

CAS NO: 1353625-73-6Bcl-2 Family inhibitors
activity
2732-3696 nmol/min·mg
Assay: ≥70% (SDS-PAGE)
Form: buffered aqueous glycerol solution
grade
PRECISIO® Kinase
Mol wt: mol wt ~70 kDa
Recombinant: expressed in E. coli
Shipped in: dry ice
Storage temp.: −70°C
Biochem/physiol Actions:
CAMK1 is a serine/threonine protein kinase that is a member of the multifunctional calcium/calmodulin-dependent protein kinase family. CAMK1 is ubiquitously expressed and phosphorylates a number of proteins including SYN1, SYN2, CREB and CFTR. In addition, Numb family of proteins may also be intracellular targets for CAMK1, and they may also be regulated by phosphorylation-dependent interaction with 14-3-3 protein. CAMK1 also plays an important role in the trafficking of HDAC7 between the cytoplasm and the nucleus. CAMK1 phosphorylates HDAC7 on multiple sites that lead to alteration in localization of HDAC7.
Legal InFormation: PRECISIO is a registered trademark of Sigma-Aldrich Co. LLC
Physical Form: Supplied in 50 mM Tris-HCl, pH 7.5, with 150 mM NaCl, 0.25mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, and 25% glycerol.
RIDADR: NONH for all modes of transport
WGK Germany: 1
Purity: ≥70% (SDS-PAGE)
activity
activity: 2732-3696 nmol/min·mg
Storage Temp.: −70°C
UNSPSC
12352200
PubMed ID:http://jpet.aspetjournals.org/content/9/8/441