Product Name: CLK1 (129-end), active, GST tagged human
Synonym: CLK/STY; STY
Product Type: Chemical
CAS NO: 2002381-25-9Procollagen C Proteinase inhibitors
activity
170-230 nmol/min·mg
Assay: ≥70% (SDS-PAGE)
Form: buffered aqueous glycerol solution
grade
PRECISIO® Kinase
Mol wt: mol wt ~66 kDa
Recombinant: expressed in baculovirus infected Sf9 cells
Shipped in: dry ice
Storage temp.: −70°C
Biochem/physiol Actions:
CLK/STY is a member of the CDC2-like (or LAMMER) family of dual specificity protein kinases. The phosphorylated serine/arginine-rich (SR) proteins involves in the pre-mRNA processing and releasing through nucleus into nucleoplasm. CLK/STY, which could phosphorylates the specific SR proteins, such as ASF/SF2, may directly regulates the activity and compartmentalization of SR splicing factors.
Legal InFormation: PRECISIO is a registered trademark of Sigma-Aldrich Co. LLC
Physical Form: Supplied in 50 mM Tris-HCl, pH 7.5, with 150 mM NaCl, 0.2 5mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, and 25% glycerol.
RIDADR: NONH for all modes of transport
WGK Germany: 1
Purity: ≥70% (SDS-PAGE)
activity
activity: 170-230 nmol/min·mg
Storage Temp.: −70°C
UNSPSC
12352200
PubMed ID:http://jpet.aspetjournals.org/content/71/3/215