ML-9

Product Name: ML-9

Synonym: 1-(5-Chloronaphthalene-1-sulfonyl)–1H-hexahydro-1,4-diazepine hydrochloride

CAS Number: 105637-50-1
Empirical Formula (Hill Notation): C₁₅H₁₇ClN₂O₂S · HCl
Molecular Weight: 361.29
MDL Number: MFCD00065525
Linear Formula: C₁₅H₁₇N₂O₂SCl · HCl
Product Type: Chemical

CAS NO: 1008763-54-9FAAH inhibitors
Assay: ≥99% (TLC)
color
white
Form: powder
InChI Key
ZNRYCIVTNLZOGI-UHFFFAOYSA-N
solubility
ethanol: soluble10 mg/mL
Storage temp.: 2-8°C
Biochem/physiol Actions:
Inhibits natural killer (NK) cell activity in a dose-dependent manner without affecting target cell binding. Shown to inhibit insulin-induced translocation of both GLUT4 and GLUT1 in a dose-dependent manner. Also reported to inhibit agonist-induced Ca2+ entry into endothelial cells and catecholamine secretion in intact and permeabilized chromaffin cells.
Features and Benefits:
This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®1280), a biologically annotated collection of high-quality, ready-to-screen compounds. Click here to learn more.
Features and Benefits:
This compound is featured on the Ca/CaMKs page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
Legal InFormation: LOPAC is a registered trademark of Sigma-Aldrich Co. LLC
Packaging:
5 mg in glass bottle
RIDADR: NONH for all modes of transport
WGK Germany: 3
Purity: ≥99% (TLC)
Storage Temp.: 2-8°C
UNSPSC
12352200
PubMed ID:http://jpet.aspetjournals.org/content/71/1/75