Thiamine pyrophosphate

Product Name: Thiamine pyrophosphate

Synonym: Aneurinepyrophosphoric acid; Cocarboxylase; Thiamine pyrophosphate chloride

CAS Number: 154-87-0
Empirical Formula (Hill Notation): C₁₂H₁₉ClN₄O₇P₂S
Molecular Weight: 460.77
Beilstein Registry Number: 3875902
EC Number: 205-836-1
MDL Number: MFCD00038740
Linear Formula: C₁₂H₁₉ClN₄O₇P₂S
Product Type: Chemical

CAS NO: RSV inhibitors
Assay: ≥95%
InChI Key
YXVCLPJQTZXJLH-UHFFFAOYSA-N
solubility
H2O: soluble50 mg/mL, clear to very slightly hazy, colorless
Storage temp.: −20°C
Application: Thiamine pyrophosphate from Sigma has been used as a substrate to assay the enzymes in golgi lamellae isolated from rat tissue.
Application: Thiamine pyrophosphate has been used in a study to assess decarboxylation mechanisms in biological systems. Thiamine pyrophosphate has also been used in a study to investigate radical reactions of thiamin pyrophosphate in 2-oxoacid oxidoreductases.
Biochem/physiol Actions:
Thiamine pyrophosphate is a coenzyme of transketolase that catalyzes the cleavage of ribulose-5-phosphate; thereby Forming D-glyceraldehyde-3-phosphate. This reaction requires the addition of an acceptor aldehyde such as ribose-5-phosphate, glyceraldehye or glycolaldehyde. The enzyme is also capable of decarboxylating hydroxypyruvate in the presence of an ′acceptor aldehyde′.
Packaging:
1, 5, 25, 100 g in poly bottle
RIDADR: NONH for all modes of transport
WGK Germany: 3
Purity: ≥95%
Storage Temp.: −20°C
UNSPSC
12352204
PubMed ID:http://jpet.aspetjournals.org/content/94/3/244