them have been enriched in GO and none had been enriched in KEGG. The functions in the genes families that had undergone contraction have been related to genetic information processing, signal transduction, and power metabolism (Supplementary Materials, Excel S2).Table 2. Numbers of gene family expansions/contractions, rapidly evolving genes (REGs), and positively chosen genes (PSGs) plus the numbers of genes enriched in GO/KEGG based on loved ones, genus, species, and connected species/taxa of fig wasps given inside the phylogenetic tree.Items Expansion Total BRD2 drug Quantity Number of Gene Families Enriched in GO/KEGG Agaonidae Genus Eu/Pl Ceratosolen Valisia Blastophaga species in Eu/Pl clade Platyscapa quadraticeps P. sp.-F. CDK16 Purity & Documentation concinna P. sp.-F. rumphill Eupristina altissima Species in Ceratosolen C. appendiculatus C. fusciceps C. gravelyi C. solmsi C. constrictus 0 0/0 10 Gene Family Contraction Total Quantity Number of Gene Families Enriched in GO/KEGG Loved ones 0/2 857 484/45 68 0/0 Total Number Quantity of Genes Enriched in GO/KEGG Total Quantity Quantity of Genes Enriched in GO/KEGG REG PSG5 two 15 0 288 165 5 24 65 36 7 110/0 0/0 0/5 0/0 15/0 20/0 0/0 0/2 0/14 2/1 0/0 0/0 77/1182 0 72 0 2 1 7 0 1 two eight 212/8 0/0 0/0 0/0 0/0 0/0 0/0 0/0 0/0 0/0 0/0 0/0 0/2572 2073 2133 2273 890 1195 1027 1258 1088 1223 1245 101214/0 4/0 17/0 1/0 0/5 1/2 0/0 2/1 0/0 1/2 0/0 0/0 0/85 81 75 110 23 39 28 22 32 39 29 2413/0 11/1 9/2 0/2 0/0 0/0 5/0 0/0 0/0 0/0 0/0 0/0 1/Insects 2021, 12,ten ofTable 2. Cont.Things Expansion Total Number Quantity of Gene Families Enriched in GO/KEGG Species in Kradibia K. tentacularis 108 88/4 Species in Valisia V. medusa 24 0/0 V. cf filippina 124 31/8 V. malayana 165 2/0 V. compacta 357 75/9 V. sp-F. langkokensis 17 0/1 Associated species of V. javana V. javana sp. 7 391 10/4 V. javana sp. two 451 79/16 V. javana sp. 8 183 1/0 V. javana sp. 1 105 4/1 V. esquirolianae 228 16/17 Species in Blastophaga Connected taxa–five taxa of 1 species in distinct hosts B. sp.-F. abeli 310 62/1 B. sp.-F. pyriformis 213 44/2 B. sp.-F. formosa 271 14/3 B. sp.-F. erecta var. 228 31/12 beecheyana 1 1 10 6 2 1 1095 1054 8 five 4 Gene Loved ones Contraction Total Number Quantity of Gene Families Enriched in GO/KEGG 0/0 0/0 0/0 0/0 0/0 0/0 257/18 29/5 0/0 0/0 0/0 1649 1864 1664 1242 1549 1773 804 803 1065 1162 1032 Total Number Number of Genes Enriched in GO/KEGG 0/0 4/0 0/0 0/0 0/0 7/4 0/0 0/2 0/0 0/1 0/3 43 63 96 28 44 91 207 177 128 177 155 Total Number Quantity of Genes Enriched in GO/KEGG 0/0 0/0 0/0 0/0 0/0 18/2 0/0 0/0 0/0 0/0 18/0 REG PSG1914 2185 2158137/16 329/31 283/25 546/533 967 286193/20 112/10 0/0 0/275 288 2273/0 0/0 0/0 0/Note: The fig wasp species related together with the two monoecious genera, Eupristina and Platyscapa, converged into a single clade within the phylogenetic tree, so we regarded as them because the clade Eu/Pl. V. javana sp. 1, 2, 7, and 8 are associated species inside the identical host with distinct distributions [9]. V. esquiroliana is the pollinator of F. triloba which can be closely associated to F. hirta. The 5 taxa of Blastophaga are closely related to every other; indeed, they’re likely a single species.The numbers of expanded and contracted gene families varied drastically among fig wasp species. This was in contrast to their closest clade with 570 (mean SE: 184.2 178.eight) and 0532 (440.0 841.0), respectively (Table two; Figure 2a,b). Though the gene families enriched in GO and KEGG have been hardly ever shared amongst species, their functions were mainly associated to signal transduction, immune technique, drug resist