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In numerous fields of medicine, investigators are looking for methods to establish which patients will respond to certain drugs in an effort to guide therapy. As an example, some cancers will respond to particular therapies if they carry faulty alleles of oncogenes whose items will be the targets of those drugs. Examples where determination of an individual’s likelihood of response depending on precise diagnosis of their illness are at the moment uncommon. One particular situation in which patient stratification has been attainable based on accessible diagnosis is human African trypanosomiasis (HAT). HAT, also referred to as sleeping sickness, is often a parasitic illness of sub-Saharan Africa affecting isolated, rural communities. Two sub-species in the parasite infect humans. Trypanosoma brucei gambiense persists in West and Central Africa and is accountable for 90 of instances, while T. b. rhodesiense exists in East and Southern Africa. Uganda could be the only nation where both sub-species of the parasite exist. Upon infection, by means of the bite of an infected tsetse fly, parasites multiply in the blood and lymphatic systems of the patient (stage 1), just before invading the central nervous method in stage 2 from the.