Name :
Hepatitis B Virus (HBV)(ayw/France/Tiollais/1979) Capsid protein (His Tag)
Biological Activity :
Background :
Hepatitis B virus (HBV) capsid assembly is a critical step in the propagation of the virus and is mediated by the core protein. The first cytoplasmic step in the formation of an infectious HBV virion is the formation of a capsid containing pregenomic RNA (pgRNA) and the viral polymerase (Pol). HBV capsid assembly is an attractive target for new antiviral therapies.
Biological Activity :
Testing in progress
Expression Host :
HBV
Source :
E. coli
Tag :
Protein Accession No. :
P03146-1
NCBI Gene ID :
Synonyms :
Synonyms :
Amino Acid Sequence :
Molecular Weight :
The recombinant Hepatitis B Virus (HBV)(ayw/France/Tiollais/1979) Capsid protein comprises 155 amino acids and has a calculated molecular mass of 17.67 kDa.
Purity :
> 95 % as determined by SDS-PAGE.
State of Matter :
Product Concentration :
Storage and Stability :
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Endotoxin Level :
Please contact us for more information.
Protein Construction :
A DNA sequence encoding the Hepatitis B Virus (HBV)(ayw/France/Tiollais/1979) Capsid protein (P03146-1) (Met1-Val149) was expressed with a polyhistidine tag at the C-terminus.
Buffer Solution :
Lyophilized from sterile 150mM NaCl, 50mM Tris, 0.5mM EDTA, pH 7.0Please contact us for any concerns or special requirements. Normally 5 % – 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hardcopy of datasheet.
Shipping :
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Redissolution :
A hardcopy of datasheet with reconstitution instructions is sent along with the products. Please refer to it for detailed information.
Synonyms :
References & Citations :
Jianming Hu,et al.Complete and Incomplete Hepatitis B Virus Particles: Formation, Function, and Application.Viruses.2017Jan Martin Berke,et al.Capsid Assembly Modulators Have a Dual Mechanism of Action in Primary Human Hepatocytes Infected with Hepatitis B Virus.Antimicrobial Agents and Chemotherapy.2017
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