Name :
Recombinant Human GPIHBP1 Protein (hFc Tag)
Biological Activity :
Background :
GPIHBP1 (Glycosylphosphatidylinositol Anchored High-Density Lipoprotein Binding Protein 1) is a Protein Coding gene. The encoded protein is a member of the lymphocyte antigen 6 (Ly6) family. GPIHBP1 is an endothelial cell protein, which binds LPL in the subendothelial spaces and transports it to the capillary lumen. GPIHBP1 was positively correlated with LPL, and GPIHBP1 is a better marker for bodyweight decrease than LPL. GPIHBP1, a glycosylphosphatidylinositol (GPI)-anchored protein of capillary endothelial cells, transports lipoprotein lipase to the capillary lumen and is essential for the lipolytic processing of triglyceride-rich lipoproteins. Diseases associated with GPIHBP1 include Hyperlipoproteinemia, Type Id, and Hyperlipoproteinemia, Type I.
Biological Activity :
Testing in progress
Expression Host :
Human
Source :
HEK293 Cells
Tag :
Protein Accession No. :
AAH63857.1
NCBI Gene ID :
Synonyms :
Synonyms :
glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1
Amino Acid Sequence :
Molecular Weight :
The recombinant human GPIHBP1 consists 378 amino acids and predicts a molecular mass of 42.2 kDa.
Purity :
> 95 % as determined by SDS-PAGE.
State of Matter :
Product Concentration :
Storage and Stability :
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Endotoxin Level :
< 1.0 EU per μg protein as determined by the LAL method.
Protein Construction :
A DNA sequence encoding the human GPIHBP1 (AAH63857.1) (Met1-Ser160) was expressed with the Fc region of human IgG1 at the C-terminus.
Buffer Solution :
Lyophilized from sterile PBS, pH 7.4.Please contact us for any concerns or special requirements. Normally 5 % – 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hardcopy of datasheet.
Shipping :
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Redissolution :
A hardcopy of datasheet with reconstitution instructions is sent along with the products. Please refer to it for detailed information.
Synonyms :
GPI-HBP1 Protein, Human; HYPL1D Protein, Human GPIHBP1 背景信息 GPIHBP1 (Glycosylphosphatidylinositol Anchored High-Density Lipoprotein Binding Protein 1) is a Protein Coding gene. The encoded protein is a member of the lymphocyte antigen 6 (Ly6) family. GPIHBP1 is an endothelial cell protein, which binds LPL in the subendothelial spaces and transports it to the capillary lumen. GPIHBP1 was positively correlated with LPL, and GPIHBP1 is a better marker for bodyweight decrease than LPL. GPIHBP1, a glycosylphosphatidylinositol (GPI)-anchored protein of capillary endothelial cells, transports lipoprotein lipase to the capillary lumen and is essential for the lipolytic processing of triglyceride-rich lipoproteins. Diseases associated with GPIHBP1 include Hyperlipoproteinemia, Type Id, and Hyperlipoproteinemia, Type I.
References & Citations :
MedChemExpress (MCE) recombinant proteins include: cytokines, enzymes, growth factors, hormones, receptors, transcription factors, antibody fragments, etc. They are often essential for supporting cell growth, stimulating cell signaling pathways, triggering or inhibiting cell differentiation; and are useful tools for elucidating protein structure and function, understanding disease onset and progression, and validating pharmaceutical targets. At MedChemExpress (MCE), we strive to provide products with only the highest quality. Protein identity, purity and biological activity are assured by our robust quality control and assurance procedures.
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
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