of its HFD dimerization partner TAF10 and our results indicate that incorporation into TFIID is important for coactivation by TAF3 of endogenous and reporter genes. Replacement of its PHD by H3K4me0-binding PHDs drastically reduced TAF3 activation function, whereas replacing with H3K4me3-binding PHDs supported transcription activation. Taken together, the results with the TAF3 mutant proteins support …
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